Learn vocabulary, terms, and more with flashcards, games, and other study tools. Bartonella infection is a major cause of unexplained fever in patients with latestage aids and should be considered in the differential diagnosis of patients with fever and cd4 counts bartonella is a relatively common cause of culturenegative endocarditis in immunocompetent and immunocompromised humans and is most commonly. This is especially important for people who have weakened immune systems. Did bartonella henselae contribute to the deaths of two. Jan 11, 2016 bartonella bacteria cause several diseases in humans. Vertebral osteomyelitis due to bartonella henselae in. Ifa testing is easily available for bartonella henselae and bartonella quintana. The transmission of bartonella to humans most often results via a cat scratch involving the claw of a cat that is contaminated with bartonellainfected flea feces. Bartonella bacteria cause several diseases in humans.
Learn and reinforce your understanding of bartonella henselae catscratch disease and bacilary angiomatosis through video. B henselae and b quintana have been linked to bacillary angiomatosis. Bartonella henselae is mostly known as the causative. Note the papillitis, peripapillary nerve fiber layer hemorrhages, macular star, and multifocal yellowwhite deep retinal lesions. We report detection of bartonella henselae dna in blood samples from 2 harbor porpoises phocoena phocoena. Another testing method is to do a bartonella dna detection test using blood from a patient. Treat cats for fleas using fipronil and other spoton treatments. May include disease information, patient result explanation, recommendations, details of testing, associated diseases, explanation of possible patient results. Bartonella henselae bloodstream infection in a boy with. Seroptype i is houston1 and serotype 2 is marseille. Bartonella henselae causes a prototypical illness characterized by fever and regional lymphadenopathy following a cat scratch or bite 8, 9.
Transverse myelitis in 2 patients with bartonella henselae infection cat scratch disease. Of the 11 currently recognized species, four have been implicated in human disease, although only two have been encountered in europe. Bartonella quintana, known for some time as a cause of trench fever, is also associated with csd and bacillary angiomatosis ba. Jan 10, 2009 there are at least four bartonella species among many, many other bartonella species that can infect cats, but b.
Cat scratch disease csd is usually selflimited, and antibiotic therapy has minimal impact on the clinical course 11, 34. Apr 18, 2015 apr 18, 2015 sketchymicro microbiology 7. Cat scratch disease csd is most commonly caused by bartonella henselae. Bartonellosis nord national organization for rare disorders. Sketchy micro bugs and picture names pod with elder at wright.
Typical csd, which occurs in 90% of cases, is characterized by low grade fever and subacute regional lymphadenitis following a recent history of cat contact. Testbankworld nursing test bank download hesi nclex. Bartonella antibody does this test have other names. Clinical and pathologic evaluation of chronic bartonella henselae or bartonella clarridgeiae infection in cats. Apr 17, 2020 bartonella henselae also lives in the feces of fleas, which can infect humans if it comes into contact with a mucous membrane or a wound, such as a cat scratch. Bartonella homochord bartonella bacilliformis, bartonella clarridgeiae, bartonella elizabethae, bartonella henselae, bartonella quintana, bartonella vinsonii, bartonella washoensis liquid if this spl contains inactivated ndcs listed by the fda initiated compliance action, they will be specified as such. Study 45 sketchy micro bugs and picture names flashcards from lindsey m. Rochalimaea named for rochalima, a similar group, were recently combined with. Acute clinical disease in cats following infection with a pathogenic strain of bartonella henselae lsu16.
Bartonella species are fastidious, gramnegative hemotropic organisms. If playback doesnt begin shortly, try restarting your device. Bartonella henselae in porpoise blood volume 11, number. Alternate approaches, such as serological testing, may be necessary to confirm infection caused by bartonella spp, other. The transmission of bartonella to humans most often results via a cat scratch involving the claw of a cat that is contaminated with bartonella infected flea feces. Our findings reinforce the need to study these organisms in patients with culturenegative, communityacquired endocarditis, especially b.
Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability. Tetracyclines in conjunction with surgical drainage if cat scratch disease tetracyclines if bacillary angiomatosis andor bacillary peilosis bartonella quintana. Cat scratch disease is a result of acute bartonella henselae infection bartonella henselae is an emerging pathogen that was first linked to cat scratch disease csd or cat scratch fever after research on infected hiv patients during the 1990s. People may feel tired, have a headache, or a fever. Bartonella bacteria are known to be carried by fleas, body lice and ticks, and theres. Cat scratch disease csd is a common zoonosis in children caused by bartonella henselae b.
Catscratch disease catscratch diseases csd is a bacterial disease caused by bartonella henselae and is spread through cat bites or scratches. Bartonella have been isolated from a range of species. A specific primer pair was derived from the b henselae 16s ribosomal rna gene fragment. Bartonella henselae antibody, igm by ifa arup lab test. Granulomatous hepatitis due to bartonella henselae infection. Bartonella henselae europattern bartonella quintana europattern. Invasomemediated uptakeelicits a massive rearrangement of actin cytoskeleton, causing aggregation. A general practitioner veterinarian typically manages most cases of bartonellosis in cats. Stable in the population common human exposure routes. Culture of bartonella quintana and bartonella henselae.
Successful treatment of bartonella henselae endocarditis in a cat. This test is intended to be used as an aid in the diagnosis of infections caused by bartonella henselae or bartonella quintana. Catscratch disease csd is an infectious disease that most often results from a scratch or bite of a cat. Is your lab looking for activities and lab gift ideas to geek out during lab week. The disease occurs most frequently in children under 15. Bartonella henselae is a bacterium responsible for a number of illnesses. Due to the fastidious growth characteristics of the bacteria, the limited sensitivity of histopathological stains, and the nonspecific histological findings on liver biopsy, the diagnosis of hepatic bartonellosis can be difficult to establish. Bartonella henselae neuroretinitis in cat scratch disease. Tania dempsey vector borne diseases bartonella duration. Increases in igg titers in serial specimens suggest active infection. As an intraerythrocytic and endotheliotropic bacterium, b. Fundus photograph showing acute bartonella henselae neuroretinitis. Bartonella henselae an overview sciencedirect topics.
Sketchymicro has everything you need to ace your microbiology exams. Vector transmission is suspected among dogs and wild canines, which are the primary reservoir hosts. A specialist in feline internal medicine andor critical care may be needed for severe cases. Other diseases have been linked to various species of bartonella. Bartonella henselae antibody, igg by ifa arup lab test.
It is mainly carried by cats and causes catscratch disease, endocarditis, and several other serious diseases in humans. Bartonella henselae can cause a transient selflimiting lymphangitis in immunocompetent. Bartonella is one of the most common genera of bacteria in the world, and bartonella henselae has a worldwide distribution. The more commonly known bartonella species include bartonella henselae, bartonella quintana, and bartonella bacilliformis. Bartonella henselae is a fastidious gramnegative rod that is the etiologic agent of csd and is associated with bacillary angiomatosis in hivinfected individuals. Suspecting optic neuritis, diagnosing bartonella cat. Bartonella henselae causes, symptoms, diagnosis, treatment, pathology. Patients exposed to other bartonella species may show considerable cross reactivity. The classification is based on the differences in the 16s ribosomal dna sequences 8. Pronunciation of bartonella henselae with 1 audio pronunciation, 2 meanings, 1 translation and more for bartonella henselae. However, a spectrum of neurological manifestations, including ischemic stroke, cerebral arteritis, transverse myelitis. Rochalimaea henselae other names i atcc 49882 atcc. Bartonella is a genus of bacteria that can cause several different infections and diseases in humans. Bartonella henselae catscratch disease and bacilary.
Bartonella henselae is an emerging pathogen that was first linked to cat scratch disease csd or cat scratch fever after research on infected hiv patients during the 1990s. Bartonella and ehrlichia clinical microbiology and infection. Cat scratch disease, also known as cat scratch fever or bartonellosis, is usually innocuous and selflimiting, though it may be treated with antibiotics. However, 5% to 10% of healthy controls exhibit a bartonella henselae and bartonella quintana titer of 1. Jun 19, 2019 bartonellosis comprises infections caused by pathogens in the genus bartonella. Symptoms typically include a nonpainful bump or blister at the site of injury and painful and swollen lymph nodes. The annual medical laboratory professionals week is just around the corner.
To investigate whether birds might be a reservoir for bartonella spp. We evaluated culturenegative, communityacquired endocarditis by using indirect immunofluorescent assays and molecular analyses for bartonella spp. Bartonella henselae is a zoonotic pathogen that usually causes a selflimiting infection in immunocompetent individuals but often causes potentially lifethreatening infections, such as bacillary angiomatosis, in immunocompromised patients. During a 5year period, we received 2,043 samples for culture of bartonella sp. Bartonella henselaeis a member of the genus bartonella, one of the most common types of bacteria in the world. They include longrecognized diseases such as carrions disease due to bartonella bacilliformis, trench fever due to bartonella quintana, and cat scratch disease csd due to bartonella henselae and bartonella clarridgeiae 25, 32, 38. Apply for and manage the va benefits and services youve earned as a veteran, servicemember, or family memberlike health care, disability, education, and more. Bartonella are gramnegative, facultative intracellular bacteria which are transmitted by fleas and ticks. One study showed they invaded the mature blood cells of humans. Bartonella henselae is a zoonotic bacteria which may cause catscratch disease, or csd, in humans.
Crossreactivity with other potentially pathogenic bartonella spp eg, b vinsonii may occur. Infection elicits a inflammatory response to activate nfkb transcription factor to regulate the innate immune response invasome causes a revolving locomotion of cell bodies, which. Successful treatment of bartonella henselae endocarditis. It is perhaps best known as the agent of cat scratch disease or cat scratch fever, but it can also cause bacillary angiomatosis, bacteremia, endocarditis, and peliosis hepatis.
Culture of bartonella quintana and bartonella henselae from. Bartonella henselae was first identified as the etiological agent of bacillary angiomatosis and peliosis in aids patients. For the detection and semiquantitation of igg antibodies to bartonella henselae and bartonella quintana in human serum. Caused by bartonella henselae infection of vascular endothelium. How to diagnose bartonella in chronic lyme disease treat. Both diagnosis of infection and research into the molecular mechanisms of pathogenesis have been hindered by the absence of a suitable liquid growth. Images of bartonella henselaebacillary angiomatosis, from the va hivaids website. Avoid rough play with cats, particularly strays and kittens, to prevent scratches. Bartonella species are now considered emerging pathogens. Bartonella medical definition merriamwebster medical. More than 30 000 cases of csd are reported annually in the united states, resulting in more than 2000 hospitalizations. Human infections due to bartonella species formerly rochalimaea species are widely considered emerging diseases.
It is a facultative intracellular microbe that targets red blood cells. Bartonellosis bartonella infection differential diagnoses. The name bartonella bacilliformis was used for the only member of the group identi. Bartonella henselae is an aerobic, oxidasenegative, and slow growing gram negative rod, slightly curved. Typical catscratch disease presents as a lymphadenopathy in a patient with.
Bartonellosis adult and adolescent opportunistic infection. Cat scratch disease testing best in bartonella testing. While on the cat, the fleas excrete feces that contain bartonella. Exposure to cats is the main risk factor for bartonella infections, especially for c.
Profile information a profile is a group of laboratory tests that are ordered and performed together under a single mayo test id. Bartonella henselae causes an important emerging infection that was first reported in 1990. These bacteria can be transmitted from a cat to a person during a scratch. Powerpoint ppt presentation free to download sandflies eggs are laid in dark humid animal burrows, cracks or crevices, or under. Bacterium is engulfed by host cell membranes to enter the endothelial cells. Bartonella henselae definition of bartonella henselae by. The arrow indicates a b henselae specific polymerase chain reaction pcr product of 279 base pairs. Although in most patients the disease resolves spontaneously within 24 months without treatment, in people with severe cases andor patients with a suppressed immune system, such as hivaids, antibiotic treatment is. Growth characteristics of bartonella henselae in a novel. Bartonellosis is an infectious bacterial disease that is caused by the bacteria bartonella henselae. Humans only reservoir, not normal flora transmission. Bartonella henselae sketchy micro flashcards quizlet.
Occasionally dog scratches or bites may be involved. Unraveling the mystery of bartonellosis july 2015 townsend. Bartonella formerly rochalimaea henselae has become firmly established as the primary etiologic agent for cat scratch disease csd. Bartonella henselaebacillary angiomatosis images hiv. Bartonella grahamii dna was amplified from a bird tick in korea.
Bartonella henselae is the most common cause of cat scratch disease csd. Catscratch disease is caused by the bacterium bartonella henselae which is believed to be spread by the cats saliva. Cat scratch disease testing cat scratch disease is a result of acute bartonella henselae infection. Normal serum specimens usually have an igg titer of less than 1. The three most common are cat scratch disease, caused by b. Bartonella formerly rochalimea includes two species, bartonella guintana and bartonella henselae.
People can get csd from the scratches of domestic or feral cats, particularly kittens. Warthinstarry stain a silver stain starry night in silver hues in the background. Cat scratch disease blood test, indirect fluorescent antibody test ifa for igm and igg against b. Bartonella causes catscratch disease, endocarditis, and. There are at least nine bartonella species that can infect humans, seven of which are zoonotic. Mar 19, 2017 bartonella henselae hillary armstrong. Bartonella ab panel, igg and igm henselae or b quintana. They are mainly transmitted via direct contact animal scratches and bites or by numerous arthropods such as sand flies, fleas, lice, biting flies, and ticks deng et al.
Cats can be infested with infected fleas that carry bartonella bacteria. Bartonella henselae serology test for igg is performed using indirect fluorescent antibody ifa test. Dailymed bartonella homochord bartonella bacilliformis. In addition, this bartonella species can cause numerous symptoms in both immunocompetent and immunocompromised individuals.
Bartonella quintana and bartonella henselae are fastidious gramnegative bacteria responsible for bacillary angiomatosis, trench fever, cat scratch disease, and endocarditis. The patient presented with rash, biquotidian fever, night sweats, and arthralgias. Publications home of jama and the specialty journals of. The substantial mobility, broad distribution, and migrations of birds make them ideal reservoir hosts for dispersal of infectious agents. The name bartonia, later bartonella bacilliformis, was used for the only member of the group identified before 1993. These patients usually lack characteristic skin papules and. By using realtime polymerase chain reaction, we directly amplified bartonella species dna from blood of a harbor porpoise stranded along the northern north carolina coast and from a preenrichment blood culture from a second harbor porpoise. The infection is commonly referred to as csd or cat scratch fever due to symptoms these bacteria can cause following a scratch from a cat. Bartonella quintana infections are now being diagnosed among the urban homeless and deprived, manifesting as trench fever, and bartonella henselae has. We present a case of a sevenyearold immunocompetent female patient who developed systemic symptoms mimicking an autoimmune rather than an infectious disease. Cat scratch disease, also known as catscratch disease, cat scratch fever, or subacute regional lymphadenitis, produces symptoms due to bacterial infection of the lymph nodes with bacteria known as bartonella henselae. Detection of a bartonella henselae specific dna target in dna isolated from the blood and cerebrospinal fluid csf of naturally infected individuals case reports before and after antimicrobial therapy. Several other species of bartonella are known to infect humans, but at present, b. Investigations showed increased inflammatory markers, leukocytosis, thrombocytosis, hypercalcemia.
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